2017, Cilt 43, Sayı 1, Sayfa(lar) 029-031

A Solitary Diffuse Neurofibroma with Bone Destruction
Hasan Emre AYDIN1, Zühtü ÖZBEK2, Deniz ARIK3, Murat VURAL2, Tevfik Erhan COŞAN2
1Dumlupınar Üniversitesi Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Kütahya
2Osmangazi Üniversitesi Tıp Fakültesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, Eskişehir
>sup>3Osmangazi Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Eskişehir
Keywords: Diffuse neurofibroma. Infiltration of the bone. Neurofibromatosis

Neurofibroma is a peripheral nerve sheath tumor of neuroectodermal origin that includes Schwann cells, perineural cells and fibroblasts. Although neurofibromas are considered benign, only one case of malign transformation has been reported. Although neurofibroma is usually located in the skin and subcutaneous tissue, it has led to infiltration of the bone in our patient which is a rare condition. Surgically, total excision can be performed in the majority of solitary neurofibromas, however total excision is difficult for diffuse neurofibromas because of invasion of surrounding tissue.